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Vir 222

Categories: Live vaccines

Freeze Dried Combined Live Vaccine – Newcastle Disease (VH strain) & Infectious Bronchitis
(Var II 1494 strain) – SPF origin

Newcastle Disease (ND), caused by Avian orthoavulavirus 1, and Infectious Bronchitis (IB), caused by Avian infectious bronchitis virus (IBV), are highly contagious poultry diseases with major economic impact. ND affects the respiratory, digestive, and nervous systems, while IB primarily targets the respiratory tract and may impair renal and reproductive function.

Control relies on vaccination and biosecurity. A live bivalent vaccine with attenuated NDV and IBV strains induces rapid mucosal and systemic immunity, promoting early protection, flock uniformity, and reduced handling stress.

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Vir 222

Information

Composition	Each dose contains live Newcastle Disease virus, lentogenic VH strain, at least 10[sup]6.5[/sup] EID50 and live attenuated Infectious Bronchitis virus, 1494 strain, at least 10 [sup]3.5[/sup] EID50.
Indications	Active immunization of chickens against Newcastle Disease and Infectious Bronchitis.
Indications for use	Use by instructions of a veterinarian. Use immediately after reconstitution with antiseptic or disinfectant free drinking water.
Administration and dosage	Spraying/Aerosol: • Prepare for each 1,000 doses 100-300 ml of non chlorinated water. • Add the reconstituted vaccine to the adequate volume of spraying water, immediately prior to use, and mix well. • The ventilation system of the poultry house should be inoperative during the spray/aerosol administration. • Direct the stream from the sprayer over the heads of the birds. • Spray at one day of age in delivery boxes: The volume applied must be accurately determined and repeatable for every box and can range from 7ml to 20ml per 100 birds depending upon the particular spray equipment in use. Droplets of 100-300μm diameter are ideal as they facilitate even coverage of birds. Drinking water: • Make sure that drinking water is free of any traces of disinfectants. • Deprive the birds of drinking water two hours before vaccination. • Prepare adequate volume of drinking water to be consumed within one to two hours. • Protect the dissolved vaccine from chlorine by adding BIOVAC'S Blue Neutrachlor® (following the instructions) or skim milk powder (50g/20L) or skim milk (0.5L/20L) to drinking water. • Stir well after mixing and allow solution to stand for 20 min before adding the vaccine. • Mix well the reconstituted vaccine in the final volume of disinfectant-free drinking water. • Let the birds consume all the vaccine-water volume before renewing water supply. Ocular route: The vaccine should be dissolved in physiological saline solution (usually 40 ml per 1,000 doses) and administered by means of a standardized dropper. Administer one drop (0.04 ml) of vaccine into the open eye of each bird.
Comments	• Vaccinate healthy birds only. • Use entire contents of the vial when first opened. • Destroy unused contents and decontaminate empty vials before discarding them. • Keep vaccination records including vaccine batch number.
Withdrawal period	Nill
Storage	Store at 2ºC-8ºC, protected from direct sunlight.
Presentation	Each box contains10 of 1,000, 2,500 or 5,000 doses.

Information

Information

Composition	Each dose contains Newcastle Disease virus, lentogenic LaSota strain, at least 10 [sup]6.5[/sup]EID50.
Indications	vaccination of poultry for immunization against Newcastle Disease.
Administration and dosage	Spraying/Aerosol: • Prepare for each 1,000 doses 100-300 ml of non chlorinated water. • Add the reconstituted vaccine to the adequate volume of spraying water, immediately prior to use, and mix well. • The ventilation system of the poultry house should be inoperative during the spray/aerosol administration. • Direct the stream from the sprayer over the heads of the birds. • Spray at one day of age in delivery boxes: The volume applied must be accurately determined and repeatable for every box and can range from 7ml to 20ml per 100 birds depending upon the particular spray equipment in use. Droplets of 100-300μm diameter are ideal as they facilitate even coverage of birds. Drinking water: • Make sure that drinking water is free of any traces of disinfectants. • Deprive the birds of drinking water two hours before vaccination. • Prepare adequate volume of drinking water to be consumed within one to two hours. • Protect the dissolved vaccine from chlorine by adding BIOVAC'S Blue Neutrachlor® (following the instructions) or skim milk powder (50g/20L) or skim milk (0.5L/20L) to drinking water to be consumed within one to two hours. • Stir well after mixing and allow solution to stand for 20 min. before adding the vaccine. • Mix well the reconstituted vaccine in the final volume of disinfectant free drinking water. • Let the birds consume all the vaccine-water volume before renewing water supply. Ocular route:>/b> The vaccine should be dissolved in physiological saline solution (usually 40 ml per 1,000 doses) and administered by means of a standardized dropper. Administer one drop (0.04ml) of vaccine into the open eye of each bird.
Comments	• Vaccinate healthy birds only. • Use entire contents of the vial when first opened. • Destroy unused contents and decontaminate empty vials before discarding them. • Keep vaccination records including vaccine batch number.
Withdrawal period	Nill
Storage	Store at 2ºC-8ºC, protected from direct sunlight.
Presentation	Each box contains 10 or 20 vials of 1,000, 2,500 or 5,000 doses.

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