Virsin 276

Categories: Inactivated Vaccines

Newcastle disease is a highly contagious viral infection of poultry caused by Avian orthoavulavirus 1. It affects the respiratory, nervous, and digestive systems, with symptoms ranging from mild respiratory signs to severe neurological disorders and high mortality. Transmission occurs through direct contact or contaminated materials. Vaccination and strict biosecurity are essential for control.

Avian Influenza H9N2 is a low pathogenic avian influenza (LPAI) virus that affects poultry, particularly chickens. It causes respiratory signs, reduced egg production, and increased susceptibility to secondary infections. Although typically associated with low mortality, co-infections can worsen disease outcomes. The virus is endemic in many regions and poses zoonotic potential. Control relies on vaccination, biosecurity, and surveillance.

Information

Indications	The vaccine is recommended for vaccination of chickens and turkeys against Newcastle and low pathogenic H9 Avian influenza.
Indications for use	Use by instructions of a veterinarian. Vaccinate only a healthy flock. Apply stringent aseptic procedure. Warm vaccine to room temperature (20ºC-25ºC), just before use. Shake well before and during use. Discard remained unused vaccine.
Administration and dosage	0.5 ml per bird. S.C.
Comments	Do not expose vaccine to direct sunlight. In case of injecting oil emulsion to human, see a physician immediately.
Storage	Store at 2ºC-8ºC. Do not freeze.
Presentation	500 ml bottle containing 1,000 doses

Information

Composition	Each dose contains Newcastle Disease virus, lentogenic LaSota strain, at least 10 [sup]6.5[/sup]EID50.
Indications	vaccination of poultry for immunization against Newcastle Disease.
Administration and dosage	Spraying/Aerosol: • Prepare for each 1,000 doses 100-300 ml of non chlorinated water. • Add the reconstituted vaccine to the adequate volume of spraying water, immediately prior to use, and mix well. • The ventilation system of the poultry house should be inoperative during the spray/aerosol administration. • Direct the stream from the sprayer over the heads of the birds. • Spray at one day of age in delivery boxes: The volume applied must be accurately determined and repeatable for every box and can range from 7ml to 20ml per 100 birds depending upon the particular spray equipment in use. Droplets of 100-300μm diameter are ideal as they facilitate even coverage of birds. Drinking water: • Make sure that drinking water is free of any traces of disinfectants. • Deprive the birds of drinking water two hours before vaccination. • Prepare adequate volume of drinking water to be consumed within one to two hours. • Protect the dissolved vaccine from chlorine by adding BIOVAC'S Blue Neutrachlor® (following the instructions) or skim milk powder (50g/20L) or skim milk (0.5L/20L) to drinking water to be consumed within one to two hours. • Stir well after mixing and allow solution to stand for 20 min. before adding the vaccine. • Mix well the reconstituted vaccine in the final volume of disinfectant free drinking water. • Let the birds consume all the vaccine-water volume before renewing water supply. Ocular route:>/b> The vaccine should be dissolved in physiological saline solution (usually 40 ml per 1,000 doses) and administered by means of a standardized dropper. Administer one drop (0.04ml) of vaccine into the open eye of each bird.
Comments	• Vaccinate healthy birds only. • Use entire contents of the vial when first opened. • Destroy unused contents and decontaminate empty vials before discarding them. • Keep vaccination records including vaccine batch number.
Withdrawal period	Nill
Storage	Store at 2ºC-8ºC, protected from direct sunlight.
Presentation	Each box contains 10 or 20 vials of 1,000, 2,500 or 5,000 doses.

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