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Production and Marketing
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Virsal DuET

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VIRSAL DuET contains the attenuated Salmonella enteritidis/MTR2 strain and the Salmonella typhimurium/MTR40 strain.
The vaccine was developed by  Biovac LTD using metabolic drift mutations. These vaccine strains are capable of invading and multiplying in the Mucosa/Gut-associated Lymphatic Tissue (M/GaLT), where they provoke protective cell-mediated and antibody immune responses that reduce sickness, carriage, and shedding of Salmonella enteritidis and Salmonella typhimurium.


Additional information

Composition

Each dose contains: 1-5*10 8.0 CFU live attenuated Salmonella Enteritidis MTR2 strain bacteria and 1-5*10 8.0 CFU live attenuated Salmonella Typhimurium MTR40 strain bacteria.
Indications

Active immunization of chickens against colonization and faecal excretion of Salmonella enteritidis and almonella typhimurium.
Indications for use

The use of the vaccine is according to veterinarian physician.
Do not exceed one dose per chicken.
For veterinary use only.
Administration and dosage

Do not give any disinfect substance, souring and other substance with anti-bacterial action 3 days before the vaccination.
For chicks vaccinated at the age of 1 day, administration should be with “first drinking water”.
Deprive the chickens from drinking 1-2 hours before vaccination (depends on weather).
Prepare adequate volume of drinking water for a flock to be consumed within 1-2 hours.
Dissolve the vaccine in disinfected or pre-boiled cooled water, with no traces of antibacterial substances or disinfectants. Use immediately after
reconstitution (no later than one hour after dissolution).
Protect the dissolved vaccine from chlorine by adding BIOVAC’S Blue Neutrachlor® to drinking water to be consumed, according to the product instructions.

After 15 minutes, add the diluted vaccine. Mix the vaccine thoroughly.
Let the birds consume all the vaccine-water volume before renewing water supply.
Comments

Wear gloves while preparing and administrating the vaccine.
• Destroy traces of vaccine and wash hands with soup after finishing administration.
• Immunization of chickens with live vaccine does not stimulate the immunity system which interfere the detection of Salmonella Pullorum and Salmonella Gallinarum.
• Accidently, swallowing the vaccine, go to physician with the vial and leaflet (the vaccine strain is sensitive to quinolones).
Contraindications

The vaccine is designated only for vaccination of healthy flock.
Future layers should not be vaccinated 3 weeks before and during laying.
Antimicrobial drugs should not be administered 3 days before and 3 days after vaccination.
The vaccine should not be administered simultaneously with other vaccines.
Vaccination does not affect the immune response to Newcastle disease. The effect on other immune responses was not tested.
Eggs should not be consumed during the period of 21 days after vaccination.
Immunization of chickens with a live vaccine does not stimulate the immunity system which interfere the detection of Salmonella Pullorum and Salmonella Gallinarum.
Storage

Store at 2ºC-8ºC, protected from direct sunlight.
Do not freeze the vaccine.
Presentation

Each box contains 10 vials of 1,000, 2,000, 4,000 or 5,000 doses.

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